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Emergency Department Decision Support using Clinical Pseudo-notes

MEME, a multimodal approach using Large Language Models and separate embeddings for EHR modalities, outperforms single modality methods and traditional machine learning for EHR tasks but has limited generalizability.

Year
2024
Venue
arXiv 2024
Authors
7
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arxiv.org/abs/2402.00160v2ARXIV-DEFAULT
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Abstract

In this work, we introduce the Multiple Embedding Model for EHR (MEME), an approach that serializes multimodal EHR tabular data into text using pseudo-notes, mimicking clinical text generation. This conversion not only preserves better representations of categorical data and learns contexts but also enables the effective employment of pretrained foundation models for rich feature representation. To address potential issues with context length, our framework encodes embeddings for each EHR modality separately. We demonstrate the effectiveness of MEME by applying it to several decision support tasks within the Emergency Department across multiple hospital systems. Our findings indicate that MEME outperforms traditional machine learning, EHR-specific foundation models, and general LLMs, highlighting its potential as a general and extendible EHR representation strategy.

Authors

7